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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd049837d7432f6d24e236bb7c0f5a6e9b3c41673c10968ca5100142c539f6d75' 
  AND token = '1F4dCTDixGq7b6r/w4s9dwEOxZ5sYoruTeqcz3ZPXFo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}