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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f754884eb733a7acb2e0812628110e518a662b1f3ac9c3c520af3b4a918dde5' 
  AND token = 'cjj2sHt8HlJs3A0ybjhOxzVC0e3b4qP6+KPXYScIzKQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}