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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fd7ce21dd781971c39df7a1edd68f067921d1b50571446fde28fef6bf90d692' 
  AND token = '2H9jPD/uUN/JmVuI0T026/57Bj9lPfrs2PCk9TrDr4g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00008

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}