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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ceaf82a8a2209a5a79f3d99d4c4d66373d20842cc611e2fa01381b9086789d7e' 
  AND token = '8Jy1XCzUh7SDDEkjXb2jP2e+aAx241qdiUIz/qc5/Ys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}