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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c5a3ba4b3111d76978f9b2f0ddc52acf3022e53079fd12867b99f9fee61a53c' 
  AND token = 'eXgsdXy8FLGMp/RYtz5zN0r6o1iG6sJ/dzyb9YZB9QU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}