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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'adb22f82b2a95caf7d33bf5871e8f00c3171ae1d1d5a5f63c2153b08c7ddfad6' 
  AND token = 'RqcEbHDTXCXAsAzggtssUDtSU91e0ctnfPNKlHoJZlg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}