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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '97e1fedee6e45345b2299a3369cdefb426dd40467c52af5fed69ce376d3ff5bb' 
  AND token = '7M4czBikddme/h0hjbvy6FoIVloc6pIcOoFHn0nDWsQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}