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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '741cb6bf072f969149cbf3728a2e7e052531f8d07dfa215dbedd6c3f6d7e5272' 
  AND token = 'kfd76WNCiBhzdCc+uNrUzPz+m0BjrXC4nTgM7T/ozyY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}