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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38322e30d1e0b66946276e4bcdc47138e9e1dc436c1f0e1c699f052f40a94949' 
  AND token = 'DvK+J2ZcfXVj5xW4IXMlVJNdEq9cJb0S79Od2LjwG7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}