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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3ecb339a43921f5d0de3f998956749cf31fcf86ac59d753232548749c7f016b' 
  AND token = 'wAqCZeQGug7eMBiq1ZadL1pQq5m6ARk93zzQXQZ28wM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}