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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6ea1d29400da72d06bd218ea90fdc7680fad297802188d95b6bb1bf63336ce2' 
  AND token = 'duY6P2KRTcyfKanhMlCDWSs8+s2PWiCkH76sZEG79rc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}