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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a54f06c62bb45d4c795d433434886954519a7a7dea27b78e1b5a5292532e7528' 
  AND token = '3rJYy4gk/thKGUHNdlQmzg8/l/V4AA5Yl0d/cagWKaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}