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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d56c1457e9217c2b07edcc483b1e5a538c4bf80974e066f4162325e9eacf9b3' 
  AND token = 'k1i9ESj2g08C7wufPJpPSyxG7bjZu9M5ZSnCfhqvZUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}