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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b8096b4796fb879759acc1ee0d2c53f3b5878f441a0b5a890bb5d3557a8cf66' 
  AND token = 'Pz3vx+i80bnm2AI3LYcdxtS7tYWLRqNCIbSMga1Qo1s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}