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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3e053be68e6e037d35d587df62b749053f97d6aba6a6cd1db7ce1436114d543' 
  AND token = 'SygUahOn8NhUEldzbkEN9+ztIAH0n2ZMCZjs8O+jPP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00008

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}