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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6dc4c118b0ab802c4c9254b148521f11582f5225509f1fc65bde26e67e6f2841' 
  AND token = 'O0vlf9GjdWXnEj1FoWc7F74oDkvLXmWFhs645ZK9jZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}