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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04424654236705f968a9d7cf001cef531c357d6d2db5403e5a99dc9a472d19b8' 
  AND token = 'wiwLiSA5IgeW3NJGqsf7+w8pTPHLe4kRR8EGbITm5o0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}