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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e06c03e1fe8556227f28bc72d3a0b8754e74a2b334f27980d7ae32a1f4cf061' 
  AND token = '/XNuBbxHdtQf2W/E4E6sc5Z9e8MoL0lOpQ9TuUCeVRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}