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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b5aff7b0a6ab0cb4919282ac73bd834c190fdc8ecc1079f37e9f4496b990358' 
  AND token = '6TnsI13cjWhHZzRMbv646TDunxVX1GxAoCflDYVSLzQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}