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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3a597a30c3c8266d757c98abb282134d4eea7d4032366e7b7066471a9df6211' 
  AND token = 'vq52iVXRQeTEcdROoEjT6d9KHOWH+vLMR0Y2h19lZs0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}