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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f65ad451a401afba8b326331faeb4b7acb9ce54b6ec430b0fcc49387061e1d23' 
  AND token = '8ZCefLiF1p5+Z4h5TRySOFb3517J5OI70v0JgCFhecI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}