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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58da8a8850e599aea103c946a88492c985132388d045e5e52ca84e1413673e7a' 
  AND token = 'xzY2QR3jaq0OTeZps7CXs1lzr7b8FtTrTqDDymm7Lhc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}