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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5807816a94164dca911740ef45c41e0c273b51a291e0fc5ba373f41565ed8a27' 
  AND token = '5FFgxKx+aQsFcq1Op9kEhzMc0JW93cZOWTwGHMNx6OU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}