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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '111babf3caf4797f5ae0680e26feba028dc87a0564e8bf1632eaa3e409aef627' 
  AND token = 'uq2SznX7hz47wLC28/HXt0eiE36B2/TnFh71xNe0m1c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}