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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '194b24c137df8860058930e6b3574531801d1e1c7ab7169f3c3a86dd4705e99f' 
  AND token = '5HantvFbebvkITFIOxd8rnFaYkPPfnFuOMa2+eKYKns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}