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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e2539d0440eb83eef263852b36fae831a8506ed66c96f000896e100c5edcb32' 
  AND token = 'V23vjEKhJkU00noUbKbn4gsgLR1x7TnET45kvucS3L0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}